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Robins Kaplan Miller & Ciresi L.L.P. is investigating six widely used Type 2 diabetes treatments related to an increased risk
of pancreatic and thyroid cancer. These treatments are: Byetta (exenatide), Victoza (liraglutide), Januvia (sitagliptin),
Janumet (sitagliptin and metformin), Onglyza (saxagliptin), and Tradjenta (lingagliptin). Byetta and Victoza are injectable
agents whereas Januvia, Janumet, Onglyza, and Tradjenta are administered orally.
All of these drugs are incretin-based therapies.1 Incretins are gastrointestinal hormones that increase rapidly after eating and signal the production of insulin.2 These drugs either mimic the effects of the incretin GLP-1 or inhibit the enzyme that breaks down naturally occurring GLP-1.3
In March of this year the FDA announced it was evaluating these drugs for an increased risk of pre-cancerous cellular changes.4 This announcement came after researchers examined pancreas cells from organ donors treated with exenatide and sitagliptin and compared them with cells from non-diabetics and diabetics on other therapies. 5 The researchers found that those on exenatide and sitagliptin for a year or more had abnormal cell growth.6
Another recent study reported a 2.9-fold increase of pancreatic cancer among those taking Byetta compared to those receiving similar treatment.7 The same study found a 2.7-fold increase in those taking Januvia.8
Our team of experienced mass tort trial attorneys, legal nurse consultants and other professionals have earned a national reputation for tirelessly fighting for justice for our clients. We welcome calls from referring attorneys or potential clients diagnosed with pancreatic or thyroid cancer after taking Byetta, Victoza, Januvia, Janumet, Onglyza, or Tradjenta.
The articles on our Website include some of the publications and papers authored by our attorneys, both before and after they joined our firm. The content of these articles should not be taken as legal advice.